Research

Our technology is rooted in over a decade of academic sleep research.  Discover the extensive list of publications in renowned scientific journals and ongoing research projects.
35 papers published
6 studies ongoing
Research

Ongoing projects

Our company has its roots in over a decade of academic research into sleeping behaviours. Discover our extensive list of published results and ongoing research.

Optimizing auditory stimuli for sleep deepening

The study refines sound-based stimuli to deepen brain waves even beyond current DeepSleep capabilities, aiming to further optimize the technology.
In progress
Stefan
Jongejan
VP of Science

Assessing DeepSleep’s impact on neurodegeneration in aging

The study evaluates whether DeepSleep can improve sleep quality and potentially slow neurodegeneration in elderly populations.
In progress
Lucia
Talamini
Founder & CSO

Innovating sleep enhancement with earable EEG

This research explores integrating ear-based EEG devices with DeepSleep technology to test its effectiveness in enhancing sleep through targeted stimulation.
In progress
Stefan
Jongejan
VP of Science

Extending automated sleep data analysis

This research develops advanced tools to automate sleep data analysis, enabling faster, more accurate, and reliable interpretations.
Peer review
Stefan
Jongejan
VP of Science

Adapting DeepSleep for partial hearing impairments

This research investigates tailored auditory stimulation methods to ensure DeepSleep’s effectiveness for individuals with partial hearing loss.
Peer review
Stefan
Jongejan
VP of Science

Boosting daytime cognitive performance and relaxation

The study explores techniques to enhance mental clarity and relaxation during the day, synergizing with DeepSleep’s nighttime benefits.
In progress
Stefan
Jongejan
VP of Science

Our partnerships

We’re pushing innovation forward, whether in our dedicated lab in Amsterdam, through at-home trials, or by teaming up with partners across the globe. Together, we’re finding new ways to make a real impact on health and well-being.
Amsterdam UMC
52
4
University Saint-Luc
50.8465573
4.351697
University of Birmingham
52.4796992
-1.9026911
Donders Institute
51.812565
5.837226
National Institute of Mental Health

National Institute
of Mental Health

50.1788667
14.419471
Harvard Medical School
42.360081
-71.058884
Monash University
-37.813629
144.963058

All research & publications

Deepening sleep using an EEG wearable featuring modeling-based closed-loop neurostimulation

Biorxiv
Stefan L. Jongejan, Anna C. van der Heijden, Lucia M. Talamini
Mar 10, 2025
Original paper
Original paper

Predicting and phase targeting brain oscillations in real-time

Biorxiv
S. Jongejan, Lucia M. Talamini, A.C. vd Heijden
Oct 12, 2024
Original paper
Original paper

Sleep-Based Memory Reactivation Boosts PTSD Treatment Outcome

Current Biology
Corresponding author Hein J.F. van Marle
Aug 19, 2024
Original paper
Original paper

Sleep Deep: Registration clinical scientific research: home sleep improvement in patients (PTSD) using DeepSleep

Amsterdam University Medical Center
Lucia Talamini
Oct 1, 2023
Original paper
Original paper

Long-term at home sleep improvement in insomnia with DeepSleep (M-CLNS Mark II)

Czech Technical University in Prague
Marek Piorecky
Jun 1, 2023
Original paper
Original paper

Boosting sleep slow waves suppresses dreaming

Biorxiv preprint
Lucia M. Talmini et Al.
Mar 10, 2023
Original paper
Original paper

Sleep as a window to target traumatic memories

Neuroscience & Biobehavioral Reviews
v Marle,Lucia M. Talamini et AL.
Mar 10, 2023
Original paper
Original paper

Sound Asleep: Processing and Retention of Slow Oscillation Phase-Targeted Stimuli

Neuroscience & Biobehavioral Reviews
Corresponding author Martin Dresler
Feb 20, 2023
Original paper
Original paper

Stabilizing Sleep Through Closed-Loop Acoustic Stimulation: Implications for Obstructive Sleep Apnea Treatment

Springer International Journal
Lucia M. Talamini
Jan 8, 2022
Original paper
Original paper

The looping lullaby: Closed-Loop Neurostimulation decreases sleepers sensitivity to environmental noise

biorxiv
Lucia Talamini 4,6,9
Aug 8, 2021
Original paper
Original paper

Sleep as a window to treat affective disorders

Current Opinion in Behavioral Sciences
Lucia M. Talamini
Mar 6, 2020
Original paper
Original paper

Manipulating memory during sleep

Sleep Medicine
Lucia T. Talamini, E. van Poppel
Dec 16, 2019
Original paper
Original paper

Slow Oscillations during Sleep Coordinate Interregional Communication in Cortical Networks

Journal of Neuroscience
Lucia M. Talamini, Roy Cox Et Al.
Dec 10, 2014
Original paper
Original paper

Sound Asleep: Processing and Retention of Slow Oscillation Phase-Targeted Stimuli

National Library of Medicine
Lucia. M. Talamini et al.
Jul 7, 2014
Original paper
Original paper