Research
Our technology is rooted in over a decade of academic sleep research. Discover the extensive list of publications in renowned scientific journals and ongoing research projects.
Deep sleep in the Dutch military
This project tests DeepSleep’s technology in military field training, assessing both sleep quality and cognitive performance.
In progress
Optimizing auditory stimuli for sleep deepening
The project refines sound-based stimuli to deepen brain waves even beyond current DeepSleep capabilities, aiming to further optimize the technology.
In progress
Innovating sleep enhancement with in-ear EEG
This project explores integrating ear-based EEG devices with DeepSleep technology to test its effectiveness in enhancing sleep through targeted stimulation.
In progress
Assessing DeepSleep’s impact on brain waste clearance
This project evaluates whether DeepSleep’s technology can accelerate sleep’s natural brain waste clearance mechanisms, thereby improving overall brain health.
In progress
Miniaturising our technology
This project focuses on embedding DeepSleep's technology onto a microcontroller platform, preparing it for integration into wearable consumer devices.
In progress
Sleep deepening in insomnia
This project deploys our technology in populations with sleep difficulties to assess whether it improves subjective sleep quality.
In progress
Embedding automated sleep data analysis
This project develops advanced tools to automate sleep data analysis, enabling faster, more accurate, and reliable interpretations.
In progress
Adapting DeepSleep for partial hearing impairments
This project investigates tailored auditory stimulation methods to ensure DeepSleep’s effectiveness for individuals with partial hearing loss.
In progress
Our partnerships
We’re pushing innovation forward, whether in our dedicated lab in Amsterdam, through at-home trials, or by teaming up with partners across the globe. Together, we’re finding new ways to make a real impact on health and well-being.
Amsterdam UMC
52
4
University Saint-Luc
50.8465573
4.351697
Donders Institute
51.812565
5.837226
National Institute of Mental Health
National Institute
of Mental Health
50.1788667
14.419471
All research & publications
Deepening sleep using an EEG wearable featuring modeling-based closed-loop neurostimulation
BioRxiv
S.L. Jongejan, A.C. van der Heijden, L.M. Talamini
Mar 10, 2025
Original paper
Original paper
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Precisely phase-locked acoustic stimuli globally enhance slow oscillations, but depress fast spindles
Biorxiv
D. P. Koller, K. Hubregtse, A.C. van der Heijden, L.M. Talamini
Mar 5, 2025
Original paper
Original paper
new
Predicting and phase targeting brain oscillations in real-time
Biorxiv
S.L. Jongejan, L.M. Talamini, A.C. van der Heijden
Oct 12, 2024
Original paper
Original paper
new
Sleep-Based Memory Reactivation Boosts PTSD Treatment Outcome
Current Biology
A.C. van der Heijden, Y.D. van der Werf, O.A. van den Heuvel, L.M. Talamini & H.J.F. van Marle
Aug 7, 2024
Original paper
Original paper
new
Boosting sleep slow waves suppresses dreaming
BioRxiv
E. Juan, C. Arslan, F. Regnath, L.M. Talamini
Mar 10, 2023
Original paper
Original paper
new
Sleep as a window to target traumatic memories
Neuroscience & Biobehavioral Reviews
A.C. van der Heijden, O.A. van den Heuvel, Y.D. van der Werf, L.M. Talamini & H.J.F. van Marle
May 7, 2022
Original paper
Original paper
new
Stabilizing Sleep Through Closed-Loop Acoustic Stimulation: Implications for Obstructive Sleep Apnea Treatment
Springer International Journal
L.M. Talamini
Jan 8, 2022
Original paper
Original paper
new
The looping lullaby: Closed-Loop Neurostimulation decreases sleepers sensitivity to environmental noise
BioRxiv
V. Pathak, E. Juan, R. van der Goot & L. M. Talamini
Aug 8, 2021
Original paper
Original paper
new
Manipulating memory during sleep
Sleep Medicine
L.M. Talamini & E. van Poppel
Dec 16, 2019
Original paper
Original paper
new
Slow Oscillations during Sleep Coordinate Interregional Communication in Cortical Networks
Journal of Neuroscience
R. Cox, J. van Driel, M. de Boer & L.M. Talamini
Dec 10, 2014
Original paper
Original paper
new
Sound Asleep: Processing and Retention of Slow Oscillation Phase-Targeted Stimuli
Plos One
R. Cox, I. Korjoukov, M. de Boer & L.M. Talamini
Jul 7, 2014
Original paper
Original paper
new